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Whereas, at higher concentrations, ROS can damage cellular biomolecules such as proteins, DNA, RNA, and lipids, finally leading to cell death [46]

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Comparable kind of reduction in oxidative stress and DNA damage was furthermore observed in Wistar albino rats (50 mg/kg/day orally for 14 days), since the biomarkers levels after biliary blocking were diminished in curcumin-treated rats